منابع مشابه
Prions and the like
Fatal Flaws by Jay Ingram, the Canadian author, writer and broadcaster, is the latest popular science book on transmissible spongiform encephalopathies. Unlike previous books—such as Deadly feasts by Richard Rhodes, The pathological protein by Philip Yam, Comment les vaches sont devenues folles by Maxime Schwartz, The family that couldn't sleep by Daniel Max and The collectors of lost souls by ...
متن کاملPrions.
The discovery of infectious proteins, denoted prions, was unexpected. After much debate over the chemical basis of heredity, resolution of this issue began with the discovery that DNA, not protein, from pneumococcus was capable of genetically transforming bacteria (Avery et al. 1944). Four decades later, the discovery that a protein could mimic viral and bacterial pathogens with respect to the ...
متن کاملPrions.
Infectious proteins (prions) are usually self-templating filamentous protein polymers (amyloids). Yeast prions are genes composed of protein and, like the multiple alleles of DNA-based genes, can have an array of "variants," each a distinct self-propagating amyloid conformation. Like the lethal mammalian prions and amyloid diseases, yeast prions may be lethal, or only mildly detrimental, and sh...
متن کاملPrions
plants are cloaked in hundreds of tiny projections, known as trichomes. These structures vary in function, shape, size and spacing from species to species, and it’s not known whether similar cellular differentiation programs are responsible for making trichomes in different plants. Trichomes are clearly visible in the scanning electron micrograph of a wild-type Nicotiana tabacum seedling above ...
متن کاملYeast and Fungal Prions.
Yeast and fungal prions are infectious proteins, most being self-propagating amyloids of normally soluble proteins. Their effects range from a very mild detriment to lethal, with specific effects dependent on the prion protein and the specific prion variant ("prion strain"). The prion amyloids of Sup35p, Ure2p, and Rnq1p are in-register, parallel, folded β-sheets, an architecture that naturally...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2008
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2008.06.011